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Abstract #28207 Published in IGR 13-1
Ocular complications of drugs used in rheumatic disease
Tam P; Taylor S; Lightman SCurrent Rheumatology Reviews 2011; 7: 61-68
Systemically administered medications have long been known to produce detectable ophthalmic signs. Some of these are benign, asymptomatic phenomena that do not require screening or regular follow-up, such as the vortex keratopathy characteristic of amiodarone use, but other medications are potentially toxic to the eye and can damage vision. Ocular toxicity is an established side-effect of several of the immunosuppressive medications in routine use in rheumatological disease, including hydroxychloroqine, but corticosteroids can also cause ocular side-effects in the form of cataract and raised intraocular pressure. Ocular side-effects often occur in a dose-related and reversible manner, but some toxicity reactions are idiosyncratic, irreversible or may progress despite cessation of treatment. (copyright) 2011 Bentham Science Publishers Ltd.
S. Lightman. UCL Institute of Ophthalmology, Moorfields Eye Hospital, 162 City Road, London EC1V 2PD, United Kingdom. s.lightman@ucl.ac.uk
Classification:
9.4.15 Glaucoma in relation to systemic disease (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders)
9.4.1 Steroid-induced glaucoma (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders)