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Abstract #46684 Published in IGR 13-3
Ocular pulse amplitude in patients with asymmetric primary open-angle glaucoma
Kac MJ; Solari HP; Velarde GC; Brazuna R; Cardoso GP; Ventura MPCurrent Eye Research 2011; 36: 727-732
Aim: To evaluate ocular pulse amplitude (OPA) using the dynamic contour tonometer (DCT) in patients with asymmetric primary open-angle glaucoma (POAG) and asymmetric intra-ocular pressure (IOP). Methods: The participants consisted of 48 patients (96 eyes) with asymmetric POAG. Three measurements of IOP and OPA were taken using DCT. The diagnosis of asymmetry required a difference of glaucomatous visual field loss greater than 6 dB in the global index MD and a difference of 5 mmHg in IOP measured by Goldmann tonometry between the more affected and the contra-lateral eye. All participants underwent full ophthalmologic clinical assessment including ultrasonic pachymetry and biometric measurements. Exclusion criteria were corneal diseases or scars, topical or systemic glaucomatous medications, and previous ocular surgery. Results: No difference (p = 0.142) was found between the axial length measurements of the better eyes group (22.95 (plus or minus) 0.91 mm) and worse eyes group (22.85 (plus or minus) 0.97 mm). There was a statistically significant difference (p = 0.011) between the central corneal thickness values of the better eyes group (537.08 (plus or minus) 29.54 (mu)m) and worse eyes group (534.40 (plus or minus) 29.87 (mu)m). The OPA values of the better eyes group (3.32 (plus or minus) 1.14 mmHg) were significantly lower (p = 0.001) than those obtained in the worse eyes group (3.83 (plus or minus) 1.27 mmHg). When correcting the OPA readings by the IOP there was no statistical difference between groups (p = 0.996). Conclusion: Higher OPA values were found in eyes with higher IOP levels and advanced glaucoma's lesions in asymmetric hypertensive POAG patients. However, after the OPA correction by the IOP levels there was no more statistical difference between eyes.
M.J. Kac. Av. Nossa Sra. de Copacabana 680/1203, Rio de Janeiro, R.J., 22050-001, Brazil.
Classification:
6.11 Bloodflow measurements (Part of: 6 Clinical examination methods)
