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Abstract #47871 Published in IGR 13-4
Risk factors for primary open-angle glaucoma in japanese subjects attending community health screenings
Ishikawa M; Sawada Y; Sato N; Yoshitomi TClinical Ophthalmology 2011; 5: 1531-1537
Background/aims: To describe risk factors associated with primary open-angle glaucoma (POAG) in Japanese subjects who participated in community health screenings. Methods: Residents of Akita, Japan, participating in a community health checkup were selected to undergo a comprehensive ophthalmic examination. Glaucoma was diagnosed based on optic disk appearance, perimetric results, and other ocular findings. Systemic blood pressure and intraocular pressure were measured and ocular perfusion pressure was calculated. Logistic regression analysis was performed to determine risk factors for POAG patients. Results and conclusion: Of the 710 subjects examined, 26 had POAG. The estimated prevalence of POAG was 3.7%. After adjusting for age, the prevalence of POAG was similar to that found in the Tajimi Study of Japanese subjects. Multivariate logistic regression analysis demonstrated that older age ((greater-than or equal to)60 years, odds ratio [OR]: 3.49), lower diastolic blood pressure ((less-than or equal to)58 mmHg, OR: 2.11), higher intraocular pressure ((greater-than or equal to)19 mmHg, OR: 4.12), and lower ocular perfusion pressure ((less-than or equal to)34 mmHg, OR: 5.78) were associated with increased risk of having POAG. These findings may be relevant for identifying high risk groups. (copyright) 2011 Ishikawa et al, publisher and licensee Dove Medical Press Ltd.
M. Ishikawa. Department of Ophthalmology, Akita Graduate University School of Medicine, Hondo 1-1-1, Akita 010-8543, Japan. Email: mako@med.akita-u.ac.jp
Classification:
1.6 Prevention and screening (Part of: 1 General aspects)
9.2.2 Other risk factors for glaucoma (Part of: 9 Clinical forms of glaucomas > 9.2 Primary open angle glaucomas)
