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Abstract #49155 Published in IGR 14-1

Comparison of optic nerve head parameters using Heidelberg retinal tomography 3 and spectral-domain optical coherence tomography

Sato S; Hirooka K; Baba T; Shiraga F
Clinical and Experimental Ophthalmology 2012; 40: 721-726


BACKGROUND: To assess the agreement between the Heidelberg Retina Tomograph (HRT) and Cirrus spectral-domain OCT (Cirrus HD-OCT) when measuring optic disc parameters. DESIGN: Prospective, cross-sectional study. PARTICIPANTS: A total of 96 glaucoma patients and 21 normal subjects were analyzed. METHODS: Optic nerve head (ONH) measurements including disc area, rim area, cup-to-disc ratio, and cup volume were obtained using both the Cirrus HD-OCT and HRT 3. MAIN OUTCOME MEASUREMENTS: Bland-Altman plots were used to evaluate the agreement between each of the optic disc parameters. RESULTS: While Cirrus HD-OCT values were smaller than HRT 3 values for the disc and rim areas, overall the Cirrus HD-OCT and HRT 3 measurements were highly correlated (r = 0.657 to 0.821). As compared to HRT 3, disc and rim areas tended to be minimized by Cirrus HD-OCT, especially when there were large disc and rim areas, although there was no relationship between the discrepancy and the level of measurement of the cup-to-disc ratio. The OCT overestimated the HRT-determined cup volume, especially when there were large cup volume CONCLUSIONS: Although Cirrus HD-OCT and HRT 3 ONH analysis are highly correlated, Bland-Altman analyses revealed that with the exception of the cup-to-disc ratio, there was poor agreement between the Cirrus HD-OCT and HRT 3 morphometric measurements. In addition, with the exception of the cup-to-disc ratio, the ONH measurements could not be directly compared between the Cirrus HD-OCT and HRT 3.

Department of Ophthalmology, Kagawa University Faculty of Medicine, Kagawa, Japan.

Full article

Classification:

2.14 Optic disc (Part of: 2 Anatomical structures in glaucoma)
6.9.1.1 Confocal Scanning Laser Ophthalmoscopy (Part of: 6 Clinical examination methods > 6.9 Computerized image analysis > 6.9.1 Laser scanning)
6.9.2.2 Posterior (Part of: 6 Clinical examination methods > 6.9 Computerized image analysis > 6.9.2 Optical coherence tomography)



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