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Abstract #51075 Published in IGR 14-3
A new strategy for diurnal intraocular pressure curve
Borrone REuropean Journal of Ophthalmology 2012; 22: 964-971
PURPOSE: To investigate whether there is agreement between intraocular pressure (IOP) readings in the supine position at 6 am upon awaking (before getting out of bed) and the IOP at 8 am, also measured in supine position after remaining 30 minutes in this position. METHODS: In a sample of 50 eyes of 50 patients (normal, glaucoma suspect, and glaucoma patients), 6 am IOP was measured in the supine position upon awaking and before getting up, while 8 am IOP was measured on the same day, also in the supine position after 30 minutes in this position. RESULTS: The IOP values at 6 am were mean 16.06±3 mmHg; median 15.5 mmHg (range 10-25.5 mmHg). For the 8 am readings, the average was 15.94±4 mmHg and the median 15 mmHg (range 10-25.5 mmHg). The difference between mean 6 and 8 am IOPs was 0.13±0.9 mmHg (confidence interval -0.14 to 0.40). Pearson correlation coefficient between the 6 and 8 am IOPs for the total sample was r=0.97 (p<0.05). There were no significant differences in behavior regarding eyes with high IOP as compared to normal IOP eyes (repeated-measure analysis of variance, p=0.72). CONCLUSIONS: The 8 am IOP readings obtained in the supine position and under the conditions described were equivalent to 6 am IOP readings (as the first measure of the diurnal pressure curve [DPC]). This new strategy for DPC will make it a widely used tool in daily practice since it spares the need for hospitalization or home measurements.
Department of Ophthalmology, University of Buenos Aires, School of Medicine, Hospital de Clínicas José de San Martín, Buenos Aires - Argentina.
Full articleClassification:
6.1.2 Fluctuation, circadian rhythms (Part of: 6 Clinical examination methods > 6.1 Intraocular pressure measurement; factors affecting IOP)