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Abstract #51397 Published in IGR 14-4
Normal tension glaucoma and Alzheimer disease: comorbidity?
Bach-Holm D; Kessing SV; Mogensen U; Forman JL; Andersen PK; Kessing LVActa Ophthalmologica 2012; 90: 683-685
PURPOSE: To investigate whether normal tension glaucoma (NTG) is associated with increased risk of developing dementia/Alzheimer disease (AD). METHODS: A total of 69 patients with NTG were identified in the case note files in the Glaucoma Clinic, University Hospital of Copenhagen (Rigshospitalet), Denmark from 1980 to 2001. The rate of a subsequent diagnosis of dementia as recorded in nationwide health care registers from 1980 to 2005 was estimated and compared with the rate for the general population [standard mortality rate (SMR) = observed number of cases of dementia/expected number of cases of dementia]. RESULTS: The 69 patients had a median age of 64 years (quartiles 57 and 73) at the time of the diagnosis, and the average follow-up period was 12.7 years. The SMR(dementia) was 0.20 (95% CI 0.01-1.11). No patient developed AD. CONCLUSION: Normal tension glaucoma was not associated with an increased risk of developing dementia/AD.
Department of Ophthalmology, University Hospital of Copenhagen, Glostrup, Denmark. daniella@dadlnet.dk
Full articleClassification:
9.2.4 Normal pressure glaucoma (Part of: 9 Clinical forms of glaucomas > 9.2 Primary open angle glaucomas)
9.4.15 Glaucoma in relation to systemic disease (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders)