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Abstract #5276 Published in IGR 1-2
Visual field responses to a hand vibration stimulus
Chai E; Goldberg I; Chia A; Chen JSurvey of Ophthalmology 1999; 43 (S1): S79-S86
Two short visual field tests were performed on 106 subjects approximately 5 minutes apart with or without a hand vibration stimulus between the field tests. There were 31 eyes in the control group (10 without glaucoma, 8 glaucoma suspects, 10 with primary open-angle glaucoma, and 3 with secondary open-angle glaucoma). There were 75 eyes in the hand vibration group (16 without glaucoma, 20 glaucoma suspects, 25 with primary open-angle glaucoma, 8 with secondary open-angle glaucoma, 3 with normal-tension glaucoma, and 3 with other forms of glaucoma). Average visual field sensitivities were significantly reduced in the arcuate zones after a hand vibration stimulus (-0.42 dB; SD, 1.26 dB) when compared with sensitivities in the arcuate zones in subjects without the hand vibration stimulus (+0.38 dB; SD, 1.53 dB; p=0.01). Multivariate analysis demonstrated a significant reduction in this response in the arcuate zone associated with the use of betaxolol (p=0.02) and timolol (p=0.047). Betaxolol was associated with significantly smaller reductions in visual field sensitivities in the paracentral zone (p=0.01). Reductions in visual field sensitivities that may be related to ocular vasospasm occurred after a hand vibration stimulus. This response may be able to be modified pharmacologically with topical ß-blockers, particularly betaxolol.
E. Chai, Sydney and Sydney Eye Hospitals, Sydney, NSW; Australia
Classification:
6.11 Bloodflow measurements (Part of: 6 Clinical examination methods)