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Abstract #5395 Published in IGR 1-2

Incidence of keratopathy following long-term instillation of single or multiple antiglaucomatous medications

Takahashi N; Hatafuku M; Nishimura T; Hosobe Y; Tazawa Y
Japanese Journal of Clinical Ophthalmology 1999; 53: 1199-1203


We reviewed the incidence of keratoepithelial disorder in 154 glaucoma eyes which received the same topical medication for 28 months. All the eyes were examined every 2 months. All the eyes received isopropylunoprostone, carteolol or timolol either singly or as combination of two agents. Keratoepithelial disorder was detected at the incidence of 12.9% to 32.5% during single medication and 40.0% to 66.7% during combined medication. The difference between single and combined medication was significant (p < 0.05). There was a tendency for the same eyes to develop recurrent keratoepitheliopathy. It appeared that the status of ocular surface may be related to this finding.

N. Takahashi, Department of Ophthalmology, School of Medicine, Iwate Medical University, 19-1 Uchimaru, Morioka-shi 020-8505; Japan


Classification:

11.1 General management, indication (Part of: 11 Medical treatment)



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