advertisement
Abstract #5407 Published in IGR 1-2
Kombinirovannaia forma proksodolola--proksofelin v lechenii bol'nykh pervichnoi otkrytougol'noi glaukomoi. (Therapy of patients with primary open-angle glaucoma with proxofelin, a combined form of proxodolol)
Ermakova VN; Malinina SL; Abdulkadyrova MZh; Filippova OM; Maliuta GDVestnik Oftalmologii 1999; 115: 3-5
Effects of an original Russian combined preparation proxofelin consisting of 1% proxodolol and 0.25% clofelin solutions on intraocular pressure, ocular hemodynamics, pupil size, depth of the anterior chamber, ocular functions, arterial pressure, and heart rate were studied in 59 patients (80 eyes) with primary open-angle glaucoma. The studies were carried out on day 1 after a single instillation of the drug and after 4-8 weeks of its regular use. Obvious hypotensive effect on intraocular pressure is due to a significant increase of the discharge efficacy coefficient (by 0.06 ± 0.008) and a 40% suppression of aqueous humor production. Comparison of the efficacies of proxofelin and proxodolol in primary open-angle glaucoma showed the advantages of the combined drug. Unlike cloefelin, the drug was well tolerated.LA: Russian
Classification:
11.3.4 Betablocker (Part of: 11 Medical treatment > 11.3 Adrenergic drugs)