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Abstract #5434 Published in IGR 1-2
The effectiveness and safety of dorzolamide 2% in addition to multiple topical antiglaucoma medications
Le HH; Chang MR; Cheng Q; Lee DA; Hartenbaum DJournal of Ocular Pharmacology and Therapeutics 1999; 15: 305-312
Dorzolamide is the first commercial topical carbonic anhydrase inhibitor approved by the Food and Drug Administration (FDA) for the treatment of glaucoma. In a prospective, open label, uncontrolled study on 245 glaucoma patients, dorzolamide significantly lowered the intraocular pressure at least 14% when used alone or in combination with one, two, or three other antiglaucoma medications over ten weeks. There were very few adverse reactions to dorzolamide. Dorzolamide is effective and safe when used alone or in combination with other topical antiglaucoma medications for the treatment of glaucoma.
Dr. D.A. Lee, Jules Stein Eye Institute, UCLA School of Medicine, 100 Stein Plaza, Los Angeles, CA 90095-7004; USA
Classification:
11.5.2 Topical (Part of: 11 Medical treatment > 11.5 Carbonic anhydrase inhibitors)
