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Abstract #56584 Published in IGR 16-1
Long-term comparison using Ex-PRESS glaucoma shunt in black and white patients
Freedman J; Ferri SCanadian Journal of Ophthalmology 2014; 49: 200-204
OBJECTIVE: To compare clinical outcomes, including patterns of failure, using the Ex-PRESS glaucoma shunt, in black and white patients with open-angle glaucoma. DESIGN: Retrospective comparative study. PARTICIPANTS: Sixty-three eyes of 50 black patients and 44 eyes of 34 white patients with open-angle glaucoma. METHODS: The Ex-PRESS shunt procedure was performed for uncontrolled glaucoma in a series of white and black patients with glaucoma. Success was defined as an intraocular pressure (IOP) between 5 and 18 mm Hg, 20% reduction from baseline, with or without suture lysis or adjuvant medication, but no additional glaucoma surgery. RESULTS: Mean length of follow-up was 29 months (range 12-81 months) for black patients and 25 months (range 12-66 months) for white patients. Mean preoperative IOP was 27 ± 7.2 and 30 ± 7.7 mm Hg for black and white patients, respectively. Mean postoperative IOP was 13 ± 3.6 and 12 ± 3.3 mm Hg for black and white patients, respectively. Using Kaplan-Meier survival curves, the success rates were 77.6% and 95% at 12 months for black and white patients, respectively. The log-rank test for comparison of survival curves indicated a significant difference between the 2 groups at 12 months (p = 0 .015) but revealed no difference at 2 years (p = 0.462). CONCLUSIONS: This study shows that patterns of failure between black and white patients treated with the Ex-PRESS glaucoma shunt change significantly with the passage of time. Black patients experience failure early, whereas white patients experience failure later at a greater pace resulting in a similar survival rate at 2 years.
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Classification:
12.8.2 With tube implant or other drainage devices (Part of: 12 Surgical treatment > 12.8 Filtering surgery)
