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Abstract #5911 Published in IGR 2-1
The use of topical aqueous suppressants in the prevention of postoperative intraocular pressure elevation after pars plana vitrectomy with long-acting gas tamponade
Mittra RA; Pollack JS; Dev S; Han DP; Mieler WF; Pulido JS; Connor TBOphthalmology 2000; 107:588-592
OBJECTIVES: To determine whether topical aqueous suppressant therapy applied after pars plana vitrectomy with gas tamponade prevents postoperative intraocular pressure (IOP) elevation. DESIGN: Prospective, nonrandomized comparative study. PARTICIPANTS: Forty-one patients who met inclusion criteria and underwent pars plana vitrectomy with gas tamponade (SF6 18-20% or C3F8 12-16%) over a one-year period. INTERVENTION: Treatment eyes received topical aqueous suppressants at the end of surgery. MAIN OUTCOME MEASURES: Postoperative IOP at four to six hours, one day, and one week. RESULTS: Twenty-one control and 20 treatment eyes met the inclusion criteria. The IOP (in mmHg) measured at four to six hours (23.05 (control, 14.73 (treatment)) and one day (23.24 (control), 17.28 (treatment)) postoperatively showed a statistically significant difference between the groups (p=0.0038) at four to six hours and a trend toward significance (p=0.057) at one day. Eleven control and three treatment eyes had an IOP spike above 25 mmHg at four to six hours or one day postoperatively (p=0.02), and six control eyes and one treatment eye had postoperative IOP greater than 30 mmHg. A pressure rise greater than 40 mmHg was seen in two control eyes but no treatment eyes. CONCLUSIONS: Use of topical aqueous suppressants after pars plana vitrectomy with long-acting gas tamponade is effective in preventing significant postoperative IOP elevation in most cases.
Dr. R.A. Mittra, Vitreoretinal Section of the Eye Institute, Medical College of Wisconsin, Milwaukee, WI, USA
Classification:
12.16 Vitrectomy (Part of: 12 Surgical treatment)
