advertisement
Abstract #59302 Published in IGR 16-3
Cataract and quality of life in patients with glaucoma
Skalicky SE; Martin KR; Fenwick E; Crowston JG; Goldberg I; McCluskey PClinical and Experimental Ophthalmology 2015; 43: 335-341
BACKGROUND: To assess the impact of cataract on quality of life (QoL) for patients with glaucoma. DESIGN: Cross-sectional study. PARTICIPANTS: Two hundred forty-two patients with mild (n = 67), moderate (n = 80) or severe (n = 45) glaucoma and 50 controls (glaucoma suspects). Patients with cataract of any severity were included. METHODS: The following data were collected: sociodemographic information, phakic/pseudophakic status, cataract grade according to the Lens Opacities Classification System (LOCS) III, visual acuity and visual field test parameters. Glaucoma severity was stratified according to binocular visual field loss. Visually significant cataract was defined as: LOCS III criteria nuclear cataract ≥3/6.9, cortical cataract ≥3/5.9 or posterior subcapsular cataract ≥2/5.9. MAIN OUTCOME MEASURES: Patients' QoL was measured using Rasch-transformed scores from the Glaucoma Activity Limitation-9 (GAL-9) questionnaire. Multiple linear regression models were used to determine the association between cataract and GAL-9 (logit) score. RESULTS: Fifty-six (23.1%) patients had at least one visually significant cataract. At least one visually significant cataract (standardized coefficient [β] 1.19, 95% confidence interval 1.04-1.34, P = 0.011) and poor visual field index (better eye) (β 1.47, 95% confidence interval 1.36-1.88, P < 0.001) were independently associated with worse GAL-9 score. CONCLUSIONS: Cataract influences glaucoma-related QoL among glaucoma patients of all severity levels and is an important cause of potentially reversible visual impairment among glaucoma patients. The Rasch-analysed GAL-9 questionnaire is a useful metric to quantify visual disability related to cataract in glaucoma patients.
Discipline of Ophthalmology, University of Sydney, Sydney, New South Wales, Australia; Centre for Eye Research Australia, University of Melbourne, Melbourne, Victoria, Australia; Department of Ophthalmology, Addenbrooke's Hospital, Cambridge, UK; Departments of Ophthalmology and Surgery, Royal Melbourne Hospital, University of Melbourne.
Full articleClassification:
1.4 Quality of life (Part of: 1 General aspects)
9.4.4.2 Glaucomas associated with cataracts (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders > 9.4.4 Glaucomas associated with disorders of the lens)
