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Abstract #6168 Published in IGR 2-2
Therapy of primary open-angle glaucoma by oftan-dipivefrin
Egorov EA; Alekseev VN; Erichev VP; Usachev VV; Simonova SV; Iakubova LVVestnik Oftalmologii 2000; 116: 32-33
Choice of the optimal hypotensive therapy with minimal side-effects remains a serious problem in the therapy of glaucoma. The efficacy and safety of oftan-dipivefrin (Sante, Finland) and glaucon (Alcon, USA) are compared in a controlled balanced randomized open parallel study preceded by a period for discharge of the previous drugs. The period of discharge was seven days, active treatment was administered for eight weeks. Sixty patients aged 61-69 years were treated. Thirty-one patients were treated by oftan-dipivefrin (group 1) and 29 by glaucon (group 2). Parallel to this, a 1% pilocarpin solution was administered in both groups. The examinations carried out during all consultations included measurements of intraocular pressure before instillations every day at the same time, evaluation of visual acuity, tonography, and study of the central and peripheral visual fields. The time course of hypotensive effects of both drugs showed a sufficient decrease in intraocular pressure in both groups; the effect of oftan-dipivefrin was more pronounced, while glaucon caused the least number of side-effects. LA: Russian
Classification:
11.3.1 Epinephrine (Part of: 11 Medical treatment > 11.3 Adrenergic drugs)