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Abstract #6339 Published in IGR 3-2
Retinal nerve fiber layer and physiological central corneal thickness
Iester M; Mermoud AJournal of Glaucoma 2001; 10: 158-162
PURPOSE: To determine the relationship between central corneal thickness and the measurement of retinal nerve fiber layer (RNFL) thickness around the optic nerve head using a confocal scanning laser polarimeter such as the Nerve Fiber Analyzer (GDx). METHODS: Forty-four eyes were recruited for this study. Each patient had a normal visual field and a healthy optic nerve head, which was assessed by slit-lamp biomicroscopy with a 90-diopter lens and by a scanning laser ophthalmoscope (Heldelberg Retina Tomograph). Using the GDx, RNFL thickness was calculated from 1.75 disc diameters, together with some standard GDx parameters, including number, symmetry, superior ratio, inferior ratio, maximum modulation, and ellipse modulation. Corneal thickness was measured with the DGH-1000 ultrasonic pachymeter. Descriptive analysis was used and Pearson's r coefficient of correlation was calculated. RESULTS: Corneal thickness was not significantly correlated to RNFL thickness, but it was significantly (p < 0.05) correlated to the other GDx parameters. CONCLUSIONS: From these data, peripapillary RNFL thickness is shown not to be significantly correlated to the corneal thickness, even if for the standard GDx parameters a significant correlation was found.
Dr A. Mermoud, Hôpital Ophtalmique Jules Gonin, 15 Avenue de France, Lausanne, CH-1004 Switzerland
Classification:
2.13 Retina and retinal nerve fibre layer (Part of: 2 Anatomical structures in glaucoma)
6.9.1 Laser scanning (Part of: 6 Clinical examination methods > 6.9 Computerized image analysis)
