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Abstract #6447 Published in IGR 3-2
Latanoprost for secondary glaucoma to uveitis
Ueki M; Kawakami T; Okuda T; Sugiyama T; Nakajima M; Ikeda TJapanese Journal of Clinical Ophthalmology 2001; 55: 1163-1166
The authors reviewed 19 eyes of 14 patients of secondary glaucoma to uveitis treated by latanoprost. There was no significant decrease in intraocular pressure (IOP) after four weeks of treatment. There was no difference in IOP decrease between eight eyes with active uveitis and 11 eyes with no active uveitis during the preceding 12 months. The outflow pressure method showed IOP reduction of 30% or more in ten eyes (53%). Uveitis was exacerbated in six of eight eyes (75%) with active uveitis. It recurred in five of 11 eyes (45%) with no active uveitis. Uveitis was exacerbated in all five eyes receiving steroid therapy. These findings illustrate that latanoprost may induce IOP decrease in some cases, but that caution is necessary because of the high rate of exacerbation or recurrence of uveitis. LA: Japanese
Dr M. Ueki, Department of Ophthalmology, Osaka Medical College, 2-7 Daigaku-cho, Takatsuki-shi, Osaka-fu 596-8686, Japan
Classification:
9.4.6 Glaucomas associated with inflammation, uveitis (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders)
11.4 Prostaglandins (Part of: 11 Medical treatment)
