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The authors describe a female patient with a history of primary open-angle glaucoma who, following treatment with topical latanoprost, a synthetic prostaglandin F2α analogue, developed hypertrichosis of the eyelashes. Hypertrichosis, a recently described side-effect of latanoprost - together with iridal pigmentation - represents a potentially permanent cosmetic side-effect associated with the use of this highly effective intraocular pressure-lowering agent. The molecular mechanism underlying latanoprost-induced hypertrichosis is unknown.
Dr B.E. Strober, Department of Medicine, New York University School of Medicine, New York, NY, USA.
11.4 Prostaglandins (Part of: 11 Medical treatment)