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Abstract #6559 Published in IGR 3-2

Autologous blood injection for marked overfiltration early after trabeculectomy with mitomycin C

Okada K; Tsukamoto H; Masumoto M; Jian K; Okada M; Mochizuki H; Mishima HK
Acta Ophthalmologica Scandinavica 2001; 79: 305-308


PURPOSE: After trabeculectomy with mitomycin C, extremely low intraocular pressure (IOP) with excess filtration may cause mypotonous maculopathy in the early postoperative period. The authors evaluated the effect of injecting autologous blood on reversing early postoperative marked hypotony after trabeculectomy with mitomycin C. METHODS: Trabeculectomy with mitomycin C was performed in 258 eyes between 1994 and 1998. Peribleb autologous blood injection was performed in five eyes in which pressure patches were ineffective in reversing excess filtration. Approximately 0.1-0.3 ml of whole unclotted blood was slowly injected at least 3 mm from the edge of the flap, using a sterile 27-gauge needle. RESULTS: None of these eyes developed hypotonous maculopathy after injection. After a mean 31-month follow-up, all eyes had well-controlled IOP, and the visual acuity in three eyes was much improved. Postoperative complications included mild IOP elevation in one eye treated with laser suture lysis, and fibrinous pupillary membrane in one eye. CONCLUSION: In the early postoperative period, autologous blood injection in effective in reversing excess filtration.

Dr I. Okada, Department of Ophthalmology, Hiroshima University School of Medicine, Hiroshima, Japan


Classification:

12.8.10 Woundhealing antifibrosis (Part of: 12 Surgical treatment > 12.8 Filtering surgery)
12.8.11 Complications, endophthalmitis (Part of: 12 Surgical treatment > 12.8 Filtering surgery)



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