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Abstract #6623 Published in IGR 4-1
Modeling passive mechanical interaction between aqueous humor and iris
Heys JJ; Barocas VH; Taravella MJJournal of Biomechanical Engineering 2001; 123: 540-547
Certain forms of glaucoma are associated with displacement of the iris from its normal contour. The authors present a mathematical model of the coupled aqueous humor-iris system that accounts for the contribution of aqueous humor flow and passive iris deformability to the iris contour. The aqueous humor is modelled as a Newtonian fluid, and the iris as a linear elastic solid. The resulting coupled equation set is solved by the finite element method with mesh motion in response to iris displacement accomplished by tracking a pseudo-solid overlying the aqueous humor. The model is used to predict the iris contour in healthy and diseased eyes. The results compare favorably with clinical observations, supporting the hypothesis that passive iris deformation can produce the iris contours observed using ultrasound biomicroscopy.
Dr. J.J. Heys, Department of Chemical Engineering, University of Colorado, Boulder, CO 80309-0424, USA. baroc001@umn.edu
Classification:
2.6 Aqueous humor dynamics (Part of: 2 Anatomical structures in glaucoma)
2.8 Iris (Part of: 2 Anatomical structures in glaucoma)