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Abstract #6726 Published in IGR 4-1

Predictive value of short-wavelength automated perimetry: a 3-year follow-up study

Polo V; Larrosa JM; Pinilla I; Perez S; Gonzalvo F; Honrubia FM
Ophthalmology 2002; 109: 761-765


PURPOSE: To determine whether structural changes in the retinal nerve fiber layer (RNFL) and functional abnormalities in short-wavelength automated perimetry (SWAP) can predict the onset of functional losses in standard automated perimetry patients suspected of having glaucoma. DESIGN: A prospective observational case series. PARTICIPANTS: A total of 160 eyes of ocular hypertensive subjects (intraocular pressure greater than 21 mmHg and normal standard automated perimetry) were included in the study. INTERVENTIONS: The subjects underwent RNFL photographic evaluation and SWAP. Standard automated perimetries were repeated after three years to evaluate glaucomatous losses. MAIN OUTCOME MEASURES: Onset of glaucomatous defects in conventional automated perimetry after three years of follow-up, with or without prior glaucomatous defects in RNFL and SWAP. RESULTS: At the start of the study, 77 eyes showed RNFL losses (48%), and 58 eyes showed abnormalities in SWAP (36%). After the three-year follow-up period, 14 of 77 eyes with RNFL losses had standard automated perimetry abnormalities (predicting sensitivity 93%), whereas 11 of 58 eyes with abnormal SWAP had standard automated perimetry losses (73% sensitivity). CONCLUSION: RNFL and SWAP losses are signs of early glaucomatous damage and can predict functional losses in standard automated perimetry.

Dr. V. Polo, Department of Ophthalmology, Miguel Servet University Hospital, P. Isabel La Catolica, 50004 Zaragoza, Spain


Classification:

6.6.2 Automated (Part of: 6 Clinical examination methods > 6.6 Visual field examination and other visual function tests)



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