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Abstract #6844 Published in IGR 4-1
Pharmacodynamics and pharmacokinetics of prostaglandins and their derivatives in eye tissues
Szalinski MR; Turno Krecicka AKlinika Oczna 2001; 103: 203-205
This paper presents the classification of prostaglandins and their receptors. The ocular distribution of the receptors and the effects of their agonists are presented. The efficacy in lowering intraocular pressure of different prostaglandins and their derivatives, especially the PGF2a group, is discussed. The history of latanoprost development is also presented. Good therapeutic index characterises two antiglaucomatous PG-derivatives: latanoprost and unoprostone.LA: Polish
Dr. M.R. Szalinski, Katedra i Zaklad Farmakologii, Akademia Medyczna, ul. Mikulicza-Radeckiego 2, 50-345 Wroclaw, Poland
Classification:
11.4 Prostaglandins (Part of: 11 Medical treatment)
