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Abstract #6844 Published in IGR 4-1

Pharmacodynamics and pharmacokinetics of prostaglandins and their derivatives in eye tissues

Szalinski MR; Turno Krecicka A
Klinika Oczna 2001; 103: 203-205


This paper presents the classification of prostaglandins and their receptors. The ocular distribution of the receptors and the effects of their agonists are presented. The efficacy in lowering intraocular pressure of different prostaglandins and their derivatives, especially the PGF2a group, is discussed. The history of latanoprost development is also presented. Good therapeutic index characterises two antiglaucomatous PG-derivatives: latanoprost and unoprostone.LA: Polish

Dr. M.R. Szalinski, Katedra i Zaklad Farmakologii, Akademia Medyczna, ul. Mikulicza-Radeckiego 2, 50-345 Wroclaw, Poland


Classification:

11.4 Prostaglandins (Part of: 11 Medical treatment)



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