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Abstract #6938 Published in IGR 4-1

Seven cases of bleb-related infection after trabeculectomy

Sugiyama W; Fukuchi T; Suda K; Nakatsue T; Tanaka Y; Hara H; Ohta A; Funaki S; Shirakashi M; Abe H
Folia Ophthalmologica Japonica / Nihon Ganka Kiyo 2001; 52: 956-959


PURPOSE: The authors evaluated the clinical course, risk factors for infection, and outcome of treatment in seven eyes of seven patients with bleb-related infection. METHODS: There were six males and one female. The mean ±1 standard deviation for the patients' ages was 58.1 ± 19.6 (range, 30-77) years, and for the time from operation until infection, 19.3 ± 17.1 (range, 2-47) months. Six of the eyes underwent trabeculectomy and adjunctive therapy with mitomycin C and two eyes underwent postoperative subconjunctival injection of 5-fluorouracil. RESULTS: Thin-walled, cystic blebs appeared before infection in all eyes. In six eyes, the blebs were avascular, and in one eye the bleb was vascular. Evaluation of the associations between clinical course, risk factors, and outcome showed that: (1) avascular blebs tend to be infected when they are localized; (2) continuous, long-term use of antibiotic drugs does not prevent infection; and (3) visual outcome and control of intraocular pressure are fairly likely to occur with early treatment. CONCLUSIONS: Currently, it is difficult to prevent all bleb-related infection. Patients must be advised of the importance of early diagnosis and treatment of bleb-related infection after trabeculectomy.LA: Japanese

Dr. W. Sugiyama, Department of Ophthalmology, Niigata University School of Medicine, 1-757 Asahimachi-dori, Niigata 951-8510, Japan


Classification:

12.8.11 Complications, endophthalmitis (Part of: 12 Surgical treatment > 12.8 Filtering surgery)



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