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Abstract #8014 Published in IGR 4-3
Sevoflurane and propofol decrease intraocular pressure equally during non-ophthalmic surgery and recovery
Sator-Katzenschlager S; Deusch E; Dolezal S; Michalek-Sauberer A; Grubmuller R; Heinze G; Wedrich ABritish Journal of Anaesthesia 2002; 89: 764-766
BACKGROUND: To provide good control of intraocular pressure (IOP) during anesthesia and surgery, the authors conducted a study comparing the effects on IOP during maintenance and recovery of sevoflurane versus propofol anaesthesia in 33 patients (ASA I-II) undergoing elective non-ophthalmic surgery. METHODS: Anesthesia was induced with propofol 2 mg kg-1, fentanyl 2 μg kg-1 and vecuronium 0.1 mg kg-1. Patients were allocated randomly to receive either propofol 4-8 mg kg-1 h-1 (group P; n = 16) or 1.5-2.5 vol% sevoflurane (group S; n = 17) for maintenance of anesthesia. Fentanyl 2-4 μg kg-1 was added if necessary. The lungs were ventilated with 50% air in oxygen. Blood pressure, heart rate, oxygen saturation and end-tidal carbon dioxide were measured before and throughout anesthesia, and in the recovery room. IOP was determined with applanation tonometry (Perkins) by one ophthalmologist blinded to the anesthetic technique. RESULTS: There was a significant decrease in IOP after induction and during maintenance of anesthesia in both groups. No significant differences in IOP between the two groups was found. CONCLUSION: Sevoflurane maintains the IOP at an equally reduced level compared with propofol.
S. Sator-Katzenschlager, MD, Department of Anaesthesiology and General Intensive Care A, University of Vienna, Austria
Classification:
12.17 Anesthesia (Part of: 12 Surgical treatment)
