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Abstract #8045 Published in IGR 4-3
Non-perforating trabecular surgery with mitomycin C in primary open-angle glaucoma
Zhong P; Dong Y; Li RChinese Ophthalmic Research 2002; 20: 351-353
OBJECTIVE: To evaluate the clinical effect of non-perforating trabecular surgery (NPTS) with mitomycin C (MMC) in primary open-angle glaucoma (POAG). METHODS: NPTS with MMC was performed on 39 eyes of 28 patients with POAG, Postoperatively, IOP, intraocular reaction, bleb appearance, complications, and visual acuity were observed. The follow-up period ranged from six to 12 months. RESULTS: The IOP in seven eyes ranged from 3.96-7.10 mmHg, and in the others was too low to be detected at five to seven days after surgery. The mean postoperative IOP was 12.43 ± 3.81 mmHg at month 1, 14.68 ± 3.73 mmHg at month 3, 15. 75 ± 4. 14 mmHg at month 6, and 17.13 ± 6. 15 mmHg at month 12. There was a statistically significant difference between mean preoperative IOP (44.53 ± 11.15 mmHg) and postoperative IOP (t = 16.08, 14.89, 13.83, and 10.24, respectively, p < 0.001). During the follow-up, IOP in six eyes was > 21 mmHg, and four of these returned to normal after laser peripheral iridoplasty and goniopuncture. At an early period after surgery, obvious diffuse blebs were seen in all eyes and, at the final visit, 77.1% of eyes had functional blebs. Complications included perforation of trabecular Descemet's membrane, peripheral iris anterior synechia, and fibrosis of trabecular Descemet's membrane. The visual acuity of all eyes had improved to a different degree. CONCLUSION: NPTS with MMC is a safe and effective anti-glaucoma surgery for POAG. LA: Chinese
P. Zhong, MD, Henan Institute of Ophthalmology, Zhengzhou 450003, China
Classification:
12.8.3 Non-perforating (Part of: 12 Surgical treatment > 12.8 Filtering surgery)
12.8.4 Using laser (Part of: 12 Surgical treatment > 12.8 Filtering surgery)
