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Abstract #8129 Published in IGR 4-3
Performance of glaucoma mass screening with only a visual field test using frequency-doubling technology perimetry
Iwasaki A; Sugita MAmerican Journal of Ophthalmology 2002; 134: 529-537
PURPOSE: To report the performance of glaucoma mass screening with only a visual field test utilizing frequency-doubling technology (FDT) perimetry in general populations. DESIGN: Hospital and population-based cross-sectional study. METHODS: This study took place in a multicenter setting. One hundred and three consecutive glaucomatous patients and 14,814 persons were randomly selected. The authors had created a glaucoma screening protocol (GSP) using FDT perimetry (FDT-GSP). Frequency-doubling technology-glaucoma screening protocol was tested on consecutive glaucoma patients diagnosed with Humphrey visual field analyzer (30-2 SITA standard), and then FDT-GSP was applied to general populations. Frequency-doubling technology-glaucoma screening protocol positive subjects were ophthalmologically diagnosed. Detection ability of FDT-GSP was determined in consecutive patients, and the positive predictive value (PPV) of FDT-GSP to detect definitive glaucoma was estimated in general populations. RESULTS: Frequency-doubling technique-glaucoma screening protocol detected 83.3 and 100% of definitive glaucoma patients with an early (mean deviation (MD) > -6 dB) and more advanced stage (MD ≤ -6 dB), respectively. In the population-based screening, there were 660 (4.5%) subjects who had positive FDT-GSP, including 512 in whom no visual field abnormalities (VFA) had been pointed out previously. Of them, 370 subjects underwent ophthalmological diagnosis. Then, 266 (71.9%, 266/370) subjects had a glaucomatous disc and 167 had definitive glaucomatous VFA. Fifty-five (14.9%) and 39 (10.5%) subjects were diagnosed as having other diseases and as normal, respectively. The PPV of FDT-GSP ranged from 32.6% (167/512)-45.1% (167/370). CONCLUSIONS: Frequency-doubling technology-based screening with only a visual field test showed reasonable performance on mass screening for detection of definitive glaucoma in this study population, considering the glaucoma prevalence.
A. Iwasaki, MD, Department of Work Systems and Health, Institute of Industrial and Ecological Science, University of Occupational and Environmental Health, Fukuoka, Japan
Classification:
1.6 Prevention and screening (Part of: 1 General aspects)
