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Abstract #8252 Published in IGR 4-3
Ultrasound biomicroscopic classification of zonules in exfoliation syndrome
Inazumi K; Takahashi D; Taniguchi T; Yamamoto TJapanese Journal of Ophthalmology 2002; 46: 502-509
PURPOSE: Exfoliation changes in the zonules or ciliary processes may be the earliest clinical signs of the exfoliation syndrome (XFS). In the present study, the authors investigated the usefulness of ultrasound biomicroscopy (UBM) for detecting the early changes of XFS in zonules. METHODS: Both eyes of 11 patients with unilateral XFS and the unilateral eyes of 11 subjects without evidence of XFS were examined using UBM. The incidence of zonular changes was compared among the XFS-positive eyes of the patients, their contralateral XFS-negative eyes, and the healthy eyes of the subjects without XFS. RESULTS: Using UBM, the authors could successfully describe the zonules in all UBM images of all subjects. In the four quadrants, the incidence of granular-type zonules was statistically different among the three groups: it was higher in XFS-positive eyes than in XFS-negative eyes, and it was higher in XFS-negative eyes than in healthy eyes. CONCLUSIONS: UBM can detect the zonular changes that may occur early in XFS. A granular-type change in the zonules may be the most typical finding in the presence of exfoliation material. Diagnostic criteria are proposed for the early detection of XFS, based on the changes found in the zonules by UBM.
K. Inazumi, MD, Glaucoma Service, Department of Ophthalmology, Gifu University School of Medicine, 40 Tsukasamachi, Gifu 500-8705, Japan
Classification:
6.12 Ultrasonography and ultrasound biomicroscopy (Part of: 6 Clinical examination methods)
9.4.4.1 Exfoliation syndrome (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders > 9.4.4 Glaucomas associated with disorders of the lens)
