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Abstract #8340 Published in IGR 4-3
Analysis of a retinal screening database to investigate the relationship between intraocular pressure and diabetic retinopathy
Barton DM; Daneshvar C; Carrington D; Buch HN; Macleod AF; West TETPractical Diabetes International 2002; 19: 203-205
AIM: To investigate whether there is a relationship between intraocular pressure (IOP) and diabetic retinopathy. METHODS: The retrospective analysis of a retinal screening database of 5838 patients with diabetes compiled over five years, providing information on 20,091 eye examinations. RESULTS: Lower mean IOP was associated with the presence of hard exudates alone (p < 0.005) and hard exudates with cotton wool spots (p < 0.001). There was no statistically significant association between IOP and other grades of retinopathy. CONCLUSIONS: The mean IOP reductions observed in exudative retinopathy, although statistically significant, were probably too small to measure conventionally. The effect of low IOP on development of retinopathy may be mediated by higher ocular perfusion pressure, but why this would be specific to exudative disease is unclear.
D.M. Barton, MD, Ward 61, Department of Diabetes and Endocrinology, City General Hospital, Stoke-on-Trent ST4 6QG, UK. davidbarton@doctors.org.uk
Classification:
9.4.15 Glaucoma in relation to systemic disease (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders)