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Abstract #8824 Published in IGR 5-1
Five-year risk of progression of primary angle closure suspects to primary angle closure: a population based study
Thomas R; George R; Parikh R; Muliyil J; Jacob ABritish Journal of Ophthalmology 2003; 87: 450-454
AIM: To report progression of primary angle closure suspects (PACS) to primary angle closure (PAC) at the five-year follow-up of a population based sample. METHODS: Eighty-two of 118 PACS who could be contacted and 110 randomly selected normals from a population-based survey in 1995 were invited for a follow-up examination in 2000. Progression to PAC was based on the development of raised IOP or synechiae in a PACS. RESULTS: Fifty of the 82 PACS contacted were examined: eleven (22%; 95% CI 9.8-34.2) developed PAC (seven synechial and four appositional); all were bilateral PACS. Two of 50 subjects previously diagnosed as PACS were reclassified as normal. One subject among the 110 normals progressed to PAC. The relative risk of progression among PACS was 24 (95% CI 3.2-182.4). There was no significant difference in axial length, anterior chamber depth, or lens thickness between those who progressed and those who did not. None of the patients developed optic disc or field damage attributable to angle closure. One angle closure suspect was diagnosed as having normotensive glaucoma. CONCLUSIONS: In this population based study of PACS, the five-year incidence of PAC was 22%; none developed functional damage. Bilateral PACS was a clinical risk factor for progression.
Dr. R. Thomas, LV Prasad Eye Institute, LV Prasad Marg, Banjara Hills, Hyderabad 500034, India. rithomas@lvpeye.stph.net
Classification:
9.3 Primary angle closure glaucomas (Part of: 9 Clinical forms of glaucomas)
