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Abstract #8870 Published in IGR 5-2

Long term follow-up of retinal nerve fiber layer thickness in eyes with optic nerve head drusen

Ocakoglu O; Ustundag C; Koyluoglu N; Oguz V; Kendiroglu G; Ozkan S
Current Eye Research 2003; 26: 277-280


PURPOSE: To investigate the effect of optic nerve head drusen (ONHD) on retinal nerve fiber layer (RNFL) thickness during a follow-up period. METHODS: Twenty-three non-glaucomatous eyes with clinically visible ONHD confirmed by colored disc photos were studied. RNFL thickness was determined by optical coherence tomography (OCT). Eyes were re-examined after an average of 18 months (ranging from 14 to 22 months). Mean RNFL thickness of each quadrant was compared with previous results at each follow-up visit. RESULTS: Mean RNFL thickness was 88.43 ± 10.2 μm at first visit and 90.35 ± 6.9 μm at follow-up visits in eyes with clinically visible ONHD. The difference between the mean RNFL thickness measured from inferior, superior, nasal and temporal quadrant at first and follow-up visits was not significant (paired t test, p > 0.05). CONCLUSIONS: The presence of drusen was found to have no effect on RNFL thickness at follow-up visits. OCT may provide a useful means to evaluate and follow up RNFL thickness in these patients.

Dr. O. Ocakoglu, Department of Ophthalmology, Istanbul University, Medical School of Cerrahpasa, Istanbul, Turkey


Classification:

10 Differential diagnosis e.g. anterior and posterior ischemic optic neuropathy



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