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PURPOSE: To investigate the effect of optic nerve head drusen (ONHD) on retinal nerve fiber layer (RNFL) thickness during a follow-up period. METHODS: Twenty-three non-glaucomatous eyes with clinically visible ONHD confirmed by colored disc photos were studied. RNFL thickness was determined by optical coherence tomography (OCT). Eyes were re-examined after an average of 18 months (ranging from 14 to 22 months). Mean RNFL thickness of each quadrant was compared with previous results at each follow-up visit. RESULTS: Mean RNFL thickness was 88.43 ± 10.2 μm at first visit and 90.35 ± 6.9 μm at follow-up visits in eyes with clinically visible ONHD. The difference between the mean RNFL thickness measured from inferior, superior, nasal and temporal quadrant at first and follow-up visits was not significant (paired t test, p > 0.05). CONCLUSIONS: The presence of drusen was found to have no effect on RNFL thickness at follow-up visits. OCT may provide a useful means to evaluate and follow up RNFL thickness in these patients.
Dr. O. Ocakoglu, Department of Ophthalmology, Istanbul University, Medical School of Cerrahpasa, Istanbul, Turkey
10 Differential diagnosis e.g. anterior and posterior ischemic optic neuropathy