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Abstract #9105 Published in IGR 5-2
A comparison of optic disc topographic parameters in patients with primary open angle glaucoma, normal tension glaucoma, and ocular hypertension
Kiriyama N; Ando A; Fukui C; Nambu H; Nishikawa M; Terauchi H; Kuwahara A; Matsumura MGraefe's Archive for Clinical and Experimental Ophthalmology 2003; 241: 541-545
BACKGROUND: Heidelberg retina tomography (HRT) findings have been used to quantitatively assess the topography of optic discs. The authors measured topographic parameters of optic discs in patients with primary open-angle glaucoma (POAG), normal tension glaucoma (NTG), and ocular hypertension (OH), using HRT to determine whether HRT topographic parameters can be used to differentiate those conditions. METHODS: Seventeen eyes of 17 patients with POAG, 23 eyes of 23 patients with NTG, and 15 eyes of 15 patients with OH were examined using HRT, and the results were analyzed by age, refractive error, and topographic parameters. RESULTS: Among the HRT parameters, the mean values for rim area, rim volume, cup disc area ratio, and classification showed significant differences between POAG, NTG, and OH eyes. The mean values for cup area, cup volume, mean retinal nerve fiber layer (RNFL) thickness, and RNFL cross-section area showed significant differences between POAG and NTG eyes, and between NTG and OH eyes, however, not between POAG and OH eyes. Cup shape measurement showed significant differences between POAG and OH, and between NTG and OH eyes, but not between POAG and NTG eyes. CONCLUSIONS: These results suggest that POAG is distinguishable from NTG and OH based on evaluations of rim area and rim volume. Patients with NTG tend to have larger cupping, smaller rims, and thinner RNFLs compared to POAG and OH patients. Thus, HRT topographic parameters are useful for differentiating patients with POAG, NTG and OH.
Dr. A. Ando, Department of Ophthalmology, Kansai Medical University, 10-15 Fumizono, Moriguchi, 570-8507 Osaka, Japan. andoak@takii.kmu.ac.jp
Classification:
2.14 Optic disc (Part of: 2 Anatomical structures in glaucoma)
6.9.1 Laser scanning (Part of: 6 Clinical examination methods > 6.9 Computerized image analysis)
9.2.4 Normal pressure glaucoma (Part of: 9 Clinical forms of glaucomas > 9.2 Primary open angle glaucomas)