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Abstract #9877 Published in IGR 5-3
Nonarteritic anterior ischemic optic neuropathy and surgery of the anterior segment: temporal relationship analysis
McCulley TJ; Lam BL; Feuer WJAmerican Journal of Ophthalmology 2003; 136: 1171-1172
PURPOSE: This study analyzes the temporal relationship between intraocular lens surgery and nonarteritic anterior ischemic optic neuropathy (NAION). DESIGN: Retrospective cohort study. METHODS: Eighteen cases of NAION in 17 subjects occurring within one year after lens-related surgery were identified with a retrospective review of patients diagnosed with NAION. The temporal relationship between NAION onset and surgery was evaluated by using an exact chi-square test of goodness of fit to compare the observed with a uniform distribution, which would be expected if intraocular surgery were not causal. RESULTS: All 18 cases occurred within six months of surgery (mean interval, 35 days; range, 1-130 days), which is significantly different from a uniform distribution (p < 0.001). CONCLUSION: These data indicate that intraocular lens surgery is associated with the occurrence of NAION.
Dr. T.J. McCulley, Department of Ophthalmology, University of California at Irvine, College of Medicine, Irvine, CA 92697-4375, USA. tmcculle@uci.edu
Classification:
10 Differential diagnosis e.g. anterior and posterior ischemic optic neuropathy
