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Abstract #9911 Published in IGR 5-3
Bilateral nongranulomatous anterior uveitis associated with bimatoprost
Packer M; Fine H; Hoffman RSJournal of Cataract and Refractive Surgery 2003; 29: 2242-2243
A 72-year-old male with long-standing bilateral glaucoma became refractory to levobunolol ophthalmic solution therapy after many years. Brimonidine was prescribed, but the patient developed a hypersensitivity several months later that was treated with loteprednol ophthalmic suspension. Bimatoprost was initiated two weeks later. Within an hour of the first dose of bimatoprost, the patient reported eye pain and photophobia that remained unresolved the following day. Examination revealed acute bilateral nongranulomatous anterior uveitis that was effectively treated with loteprednol. While observations in human and animal models suggest an association between certain prostaglandin-like agents and intraocular inflammation, this report is one of the first to suggest a link between bimatoprost and intraocular inflammatory reaction.
Dr. M. Packer, Oregon Eye Institute, 1550 Oak Street, Suite 5, Eugene, OR 97401, USA
Classification:
11.4 Prostaglandins (Part of: 11 Medical treatment)
