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Abstract #19012 Published in IGR 3-1
The impact of glaucoma medication on parameters of ocular perfusion
Harris A; Jonescu-Cuypers CPCurrent Opinions in Ophthalmology 2001; 12: 131-137
While intraocular pressure is considered a major risk factor in glaucoma, growing evidence now indicates that ocular ischemia also plays a major role. By virtue of this, and because many existing medications are able to interact with vasculature, altering ocular blood flow, it is essential that current and future medications for glaucoma be evaluated for their effect on ocular circulation. The authors review published papers examining the effect of topical and some systemic medications on ocular blood flow, focusing mostly on data from the human eye. The authors provide a comprehensive review on the effect of subclasses of medications (e.g., carbonic anhydrase inhibitors, beta-blockers, alpha-adrenergic agonists, and prostaglandin analogues on optic nerve head, and on retinal, choroidal, and retrobulbar circulation. The various claims for enhancements or reduction of ocular circulation within each class of medication are reviewed and evaluated.
Dr. A. Harris, Letzter Chair of Ophthalmology, Department of Ophthalmology, Indiana University School of Medicine, 702 Rotary Circle, Indianapolis, IN 46202, USA
Classification:
6.8.2 Posterior segment (Part of: 6 Clinical examination methods > 6.8 Photography)
