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Abstract #11760 Published in IGR 7-1
Improvement of spatial contrast sensitivity threshold after surgical reduction of intraocular pressure in unilateral high-tension glaucoma
Gandolfi SA; Cimino L; Sangermani C; Ungaro N; Mora P; Tardini MGInvestigative Ophthalmology and Visual Science 2005; 46: 197-201
PURPOSE: To measure the effect of a surgical reduction of IOP on the spatial contrast sensitivity threshold in eyes showing a considerably increased IOP but no glaucomatous visual field defect, on white-on-white computer-assisted static perimetry. METHODS: Prospective clinical trial, lasting 36 months; 10 consecutive subjects with untreated IOP ≥ 30 mmHg in one eye and ≤18 mmHg in the fellow eye, no evidence of field damage in both eyes, best corrected visual acuity ≥20/20 in both eyes, and scheduled for a primary trabeculectomy in the eye showing a high IOP. The spatial contrast sensitivity threshold was measured before surgery and at each follow-up visit. RESULTS: Preoperative spatial contrast sensitivity was worse in those eyes bearing a high IOP relative to the normal fellow eyes (paired samples t-test, P < 0.0005). An improvement of contrast sensitivity threshold, exceeding the 95% confidence limits of the preoperative test-retest variability, was observed at 3, 6, and 12 cyc/deg in each surgical eye at the end of follow-up. No change was observed in the fellow untreated normal eyes. The improvement correlated directly with the amount of decrease in pressure obtained by surgery. CONCLUSIONS: Eyes with no field defects on white-on-white computer-assisted static perimetry, but bearing a IOP ≥ 30 mmHg, show a decreased spatial contrast sensitivity. A surgically obtained reduction of IOP is paralleled by an improvement of spatial contrast sensitivity.
Dr. S.A. Gandolfi, Glaucoma Service, Institute of Ophthalmology, University of Parma, Parma, Italy. s.gandolfi@rsadvnet.it
Classification:
6.6.3 Special methods (e.g. color, contrast, SWAP etc.) (Part of: 6 Clinical examination methods > 6.6 Visual field examination and other visual function tests)
12.8.1 Without tube implant (Part of: 12 Surgical treatment > 12.8 Filtering surgery)