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Abstract #24451 Published in IGR 11-3

Efficacy evaluation using sandwich style human amniotic membrane transplantation for refractory glaucoma

Lu J; Xing Q; Xu M; Meng Y-F; Gu Z
International Journal of Ophthalmology 2009; 9: 1087-1089


AIM: To evaluate of using ultrasound biomicroscopy (UBM) in trabeculectomy combined with sandwich style human amniotic membrane transplantation for refractory glaucoma. METHODS: We analyzed retrospectively 49 patients (50eyes) with refractory glaucoma, who undertaken trabeculectomy and human amniotic membrane transplantation between scleral and conjunctional flap (sandwich style) to maintain filtration trap. RESULTS: The follow-up time was 6-12 months, 85.2% of patients received whole follow-up. the intraocular pressure decreased from 46.38 ± 0.12mmHg before operation to 18.86 ± 3.80mmHg (t = 48.56, P < 0.05) 12 months after operation. The IOP before and after surgery had significant differences. 91.7% had functional filtration trap. No one had rejection and serious complications. All patients formed anterior liquid cavity in UBM, in follow-up time the cavity of anterior scleral pool had no obvious changes, the average width was 1.976 ± 0.618mm, the height 0. 295 ± 0.137mm. About 9 months postoperation the amniotic membrane had melt, in UBM there had no liquid cavity after scleral pool, but the filtration trap was good. CONCLUSION: Sandwich style human amniotic membrane transplantation is safe and effective for refractory glaucoma. UBM is useful in long-term follow-up after surgery. LA: Chinese

Dr. Q. Xing, Department of Ophthalmology, Second People's Hospital of Changshu City, Changshu 215500, Jiangsu Province, China. xingqian172@163.com


Classification:

12.8.5 Other (Part of: 12 Surgical treatment > 12.8 Filtering surgery)
6.12 Ultrasonography and ultrasound biomicroscopy (Part of: 6 Clinical examination methods)



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