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Abstract #19798 Published in IGR 9-4

Histopathological changes in pseudoexfoliative syndrome

Sollosy M; Preda M; Simionescu C; Margaritescu C
Oftalmologia 2007; 51: 100-107


PURPOSE: The purpose of this study was to analyse the structural modifications of the anterior structures of the human eyes with exfoliation syndrome in optic microscopy. MATERIAL AND METHOD: We used bulbar conjunctival fragments and the anterior part of the eyes that were eviscerated for the complications of exfoliative glaucoma. For the optic microscopy the human specimens were preserved in paraffin and stained with hematoxiline-eosine, PAS and Congo red method. RESULTS: We have demonstrated in this study using this three colorations that the abnormal material is exfoliative material and not amyloid in all the ocular structures that were studied (conjunctiva, cornea, lens and ciliary body). CONCLUSIONS: All the anterior structures of the eyes that were examined present typical histopathological alterations of the exfoliation syndrome. The Congo red coloration demonstrate that the abnormal material present in all the structures that were examined is exfoliation material and not amyloid. LA: Romanian


Classification:

9.4.4.1 Exfoliation syndrome (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders > 9.4.4 Glaucomas associated with disorders of the lens)
3.1 Microscopy (Part of: 3 Laboratory methods)



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