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Abstract #22527 Published in IGR 11-1
Choroidal expansion during the water drinking test
Vasconcelos De Moraes CG; Castro Reis AS; de Sá Cavalcante AF; Sano ME; Susanna R JrGraefe's Archive for Clinical and Experimental Ophthalmology 2009; 247: 385-389
See also comment(s) by Helen Danesh-Meyer •
PURPOSE: To evaluate the correlation between intraocular pressure (IOP) rise, ocular pulse amplitude (OPA), and choroidal thickness (ChT) during the water drinking test (WDT). METHODS: Primary open-angle glaucoma (POAG) patients were submitted to the WDT followed by serial IOP measurements using dynamic contour tonometry (DCT), Goldman tonometry (GAT), and ChT measurements using ultrasonographic A and B-scan (USG). A control group not submitted to the test was also evaluated using DCT, GAT, and USG. Intraclass correlation coefficient (ICC) was calculated in the control group in order to assess the reproducibility of measurements. Spearman's coefficient (rho) was used to assess the correlation between the variables. RESULTS: Thirty eyes were included in the study. There was a significant IOP rise during the WDT using both GAT and DCT (p < 0.001). The OPA and ChT measurements also increased significantly (p < 0.001). Spearman's correlation between the OPA values and ChT measurements was significant and moderate (ρ = 0.40, p = 0.005). The average increase of OPA and ChT measurements occurred 15 min before the IOP rise. CONCLUSIONS: There was a significant increase of OPA and ChT measurements followed by an IOP rise during the WDT. Increased choroidal volume due to hemodynamic forces may be enrolled in the mechanism of IOP elevation during this stress test.
Dr. c.G. Vasconcelos De Moraes, Glaucoma Service, Department of Ophthalmology, University of Sao Paulo School of Medicine, Sao Paulo, SP, Brazil, gustavousp@gmail.com
Classification:
6.13 Provocative tests (Part of: 6 Clinical examination methods)
6.11 Bloodflow measurements (Part of: 6 Clinical examination methods)
2.12 Choroid, peripapillary choroid, peripapillary atrophy (Part of: 2 Anatomical structures in glaucoma)