advertisement
Abstract #16976 Published in IGR 9-1
Role of early trabeculectomy in primary open-angle glaucoma in the developing world
Anand A; Negi S; Khokhar S; Kumar H; Gupta SK; Murthy GV; Sharma TKEye 2007; 21: 40-45
See also comment(s) by Kuldev Singh •
BACKGROUND: The lack of prospective data comparing early surgery and medical management in primary open-angle glaucoma (POAG) in the developing world led us to conduct a small randomised controlled clinical trial to evaluate acceptance and effectiveness of early trabeculectomy in these patients. METHODS: A total of 60 patients with moderately advanced POAG were randomised into three groups (Group I-Conventional medical management, Group II-Option for early trabeculectomy, Group III-Received an educational package about their disease before an option for early trabeculectomy). The patients were followed up for a period of 6 months for visual acuity, intraocular pressure (IOP), and subjective satisfaction. RESULTS: The three study groups were statistically similar with respect to mean IOP, demographic, and socio-economic profile. Thirty-five percent of the patients accepted early surgery when offered a choice between early surgery and medical management in one of the groups. Sixty-five percent of patients in another group expressed willingness for an early surgery after receiving health education on glaucoma. The mean IOP in the operated eyes was lower than the medically treated eyes at 2 weeks (16.6 vs 23.0 mmHg), 6 months (18.5 vs 22.8 mmHg), and 1-year review (17.9 vs 22.3 mmHg) (P < 0.001). No significant difference was seen among the groups with regard to visual acuity and subjective satisfaction. CONCLUSION: There is a reasonable acceptance of early surgery in POAG patients in the developing world and increases on educating patients about their disease. Early surgery offers better IOP control with no long-term subjective adverse effects.
Dr. A. Anand, Dr RP Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi 110029, India. aasshishanand@hotmail.com
Classification:
12.1 General management, indication (Part of: 12 Surgical treatment)
11.1 General management, indication (Part of: 11 Medical treatment)
12.8.1 Without tube implant (Part of: 12 Surgical treatment > 12.8 Filtering surgery)
