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Abstract #20913 Published in IGR 10-2
Anterior chamber depth and chamber angle and their associations with ocular and general parameters: The Beijing Eye Study
Xu L; Cao WF; Wang YX; Chen CX; Jonas JBAmerican Journal of Ophthalmology 2008; 145: 929-936
See also comment(s) by David Friedman •
PURPOSE: To investigate the normative data of anterior chamber depth (ACD) and angle width and their associations in Chinese adults. DESIGN: Population-based study. METHODS: The Beijing Eye Study 2006 included 3,251 subjects (73.3%) (aged 45+ years) out of 4,439 subjects who participated in the 2001 survey and who returned for reexamination. The subjects underwent an ophthalmologic examination including measurement of the anterior chamber dimensions by slit-lamp-based optical coherence tomography (OCT). RESULTS: Out of the 3,251 subjects, OCT measurements were available for 2,985 subjects (91.8%). Mean ACD measured 2.42 ± 0.34 mm and the mean anterior chamber angle (ACA) was 38.3 ± 16.3 degrees. In multivariate analysis, a shallow chamber depth was significantly associated with age (P < .001), hyperopic refractive error (P < .001), female gender (P < .001), short body stature (P = .003), nuclear cataract (P = .03), central corneal thickness [CCT] (P < .001), large optic disk (P < .001), and presence of chronic angle-closure glaucoma (P < .001). Correspondingly, a narrow ACA was associated with age (P < .001), female gender (P < .001), hyperopia (P < .001), nuclear cataract (P < .001), short body stature (P = .001), large optic disk (P < .001), and angle-closure glaucoma (P < .001). Chamber depth and angle width were not associated with presence of age-related maculopathy and diabetic retinopathy. CONCLUSIONS: A shallow anterior chamber and a narrow chamber angle in Chinese adults are associated with age, female gender, hyperopia, nuclear cataract, small optic disk, short body stature, CCT, and chronic angle-closure glaucoma. These data may be helpful to explain anatomic relationships of the anterior segment of the eye, and to elucidate risk factors of angle-closure glaucoma.
Dr. L. Xu, Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing, China
Classification:
2.4 Anterior chamber angle (Part of: 2 Anatomical structures in glaucoma)
1.1 Epidemiology (Part of: 1 General aspects)