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Abstract #11546 Published in IGR 6-3
Corticosteroids are the main culprits in drug-induced glaucoma
No authors listedDrugs and Therapy Perspectives 2004; 20: 19-22
Drug-induced glaucoma, a form of secondary glaucoma, is brought about by specific systemic or topical medications. Open-angle glaucoma is generally caused or exacerbated by corticosteroids (glucocorticoids). Approximately 18-36% of the general population and 46-92% of patients with primary open-angle glaucoma experience an increase in intraocular pressure (IOP) after topical ocular administration of corticosteroids for 2-4 weeks. Angle-closure drug-induced glaucoma is a painful condition characterised by an acute onset and sudden major increase in IOP. Various drugs may be implicated in its pathogenesis (e.g. adrenergic agonists, antidepressants, antihistamines and sulpha-based compounds).
Classification:
9.4.1 Steroid-induced glaucoma (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders)