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  • 1 General aspects

  •      1.1 Epidemiology
  •      1.2 Population genetics
  •      1.3 Pathogenesis
  •      1.4 Quality of life
  •      1.5 Glaucomas as cause of blindness
  •      1.6 Prevention and screening
  • 2 Anatomical structures in glaucoma

  •      2.1 Conjunctiva
  •      2.2 Cornea
  •      2.3 Sclera
  •      2.4 Anterior chamber angle
  •      2.5 Meshwork
  •          2.5.1 Trabecular meshwork
  •          2.5.2 Schlemms canal
  •          2.5.3 Scleral outlet channels
  •      2.6 Aqueous humor dynamics
  •          2.6.1 Production
  •          2.6.2 Outflow
  •              2.6.2.1 Trabecular meshwork
  •              2.6.2.2 Uveoscleral
  •          2.6.3 Compostion
  •      2.7 Episcleral veins and venous pressure
  •      2.8 Iris
  •      2.9 Ciliary body
  •      2.10 Lens
  •      2.11 Vitreous body
  •      2.12 Choroid, peripapillary choroid, peripapillary atrophy
  •      2.13 Retina and retinal nerve fibre layer
  •      2.14 Optic disc
  •      2.15 Optic nerve
  •      2.16 Chiasma and retrochiasmal central nervous system
  •      2.17 Stem cells
  •      2.20 Other
  • 3 Laboratory methods

  •      3.1 Microscopy
  •      3.2 Electron microscopy
  •      3.3 Immunohistochemistry
  •      3.4 Molecular genetics
  •          3.4.1 Linkage studies
  •          3.4.2 Gene studies
  •      3.5 Molecular biology incl. SiRNA
  •      3.6 Cellular biology
  •      3.7 Biochemistry
  •      3.8 Pharmacology
  •      3.9 Pathophysiology
  •      3.10 Immunobiology
  •      3.11 Pharmacogenetics
  •      3.12 Proteomics
  •      3.13 In vivo imaging
  •          3.13.1 Laser Scanning
  •              3.13.1.1 Confocal Scanning Laser Ophthalmoscopy
  •              3.13.1.2 Confocal Scanning Laser Polarimetry
  •          3.13.2 Optical Coherence Tomography
  •              3.13.2.1 Anterior Segment
  •              3.13.2.2 Posterior Segment
  •          3.13.3 RGC Imaging
  •          3.13.4 Other
  •      3.20 Other
  • 4 Tissue culture of ocular cells

  • 5 Experimental glaucoma; animal models

  •      5.1 Rodent
  •      5.2 Primates
  •      5.3 Other
  • 6 Clinical examination methods

  •      6.1 Intraocular pressure measurement; factors affecting IOP
  •          6.1.1 Devices, techniques
  •          6.1.2 Fluctuation, circadian rhythms
  •          6.1.3 Factors affecting IOP
  •      6.2 Tonography, aqueous flow measurement (see also 2.6)
  •      6.3 Biomicroscopy (slitlamp)
  •          6.3.1 Anterior segment
  •          6.3.2 Posterior segment
  •      6.4 Gonioscopy
  •      6.5 Ophthalmoscopy
  •      6.6 Visual field examination and other visual function tests
  •          6.6.1 Conventional manual
  •          6.6.2 Automated
  •          6.6.3 Special methods (e.g. color, contrast, SWAP etc.)
  •      6.7 Electro-ophthalmodiagnosis
  •      6.8 Photography
  •          6.8.1 Anterior segment
  •          6.8.2 Posterior segment
  •      6.9 Computerized image analysis
  •          6.9.1 Laser scanning
  •              6.9.1.1 Confocal Scanning Laser Ophthalmoscopy
  •              6.9.1.2 Confocal Scanning Laser Polarimetry
  •          6.9.2 Optical coherence tomography
  •              6.9.2.1 Anterior
  •              6.9.2.2 Posterior
  •          6.9.5 Other
  •      6.10 Fluorescein (ICG) angiography
  •          6.10.1 Anterior segment
  •          6.10.2 Posterior segment
  •      6.11 Bloodflow measurements
  •      6.12 Ultrasonography and ultrasound biomicroscopy
  •      6.13 Provocative tests
  •      6.19 Telemedicine
  •      6.20 Progression
  •      6.30 Other
  • 8 Refractive errors in relation to glaucoma

  •      8.1 Myopia
  •      8.2 Hypermetropia
  •      8.3 Contact lenses
  •      8.4 Refractive surgical procedures
  •      8.5 Other
  • 9 Clinical forms of glaucomas

  •      9.1 Developmental glaucomas
  •          9.1.1 Congenital glaucoma, Buphthalmos
  •          9.1.2 Juvenile glaucoma
  •          9.1.3 Syndromes of Axenfeld, Rieger, Peters, aniridia
  •          9.1.4 Other
  •      9.2 Primary open angle glaucomas
  •          9.2.1 Ocular hypertension
  •          9.2.2 Other risk factors for glaucoma
  •          9.2.3 Open angle glaucoma with elevated IOP
  •          9.2.4 Normal pressure glaucoma
  •      9.3 Primary angle closure glaucomas
  •          9.3.1 Acute primary angle closure glaucoma (pupillary block)
  •          9.3.2 Chronic primary angle closure glaucoma (pupillary block)
  •          9.3.3 Plateau iris syndrome
  •          9.3.4 Primary angle closure suspect
  •          9.3.5 Primary angle closure
  •          9.3.10 Other
  •      9.4 Glaucomas associated with other ocular and systemic disorders
  •          9.4.1 Steroid-induced glaucoma
  •          9.4.2 Glaucomas associated with disorders of the cornea, conjunctiva, sclera
  •              9.4.2.1 Iridocorneal endothelial syndrome (ICE, incl. irisatrophy)
  •              9.4.2.2 Posterior polymorphous dystrophy
  •              9.4.2.3 Fuchs' endothelial dystrophy
  •              9.4.2.5 Other
  •          9.4.3 Glaucomas associated with disorders of the iris and ciliary body
  •              9.4.3.1 Pigmentary glaucoma
  •              9.4.3.5 Other
  •          9.4.4 Glaucomas associated with disorders of the lens
  •              9.4.4.1 Exfoliation syndrome
  •              9.4.4.2 Glaucomas associated with cataracts
  •              9.4.4.3 Glaucomas associated with lens dislocation
  •              9.4.4.5 Other
  •          9.4.5 Glaucomas associated with disorders of the retina, choroid and vitreous
  •              9.4.5.1 Neovascular glaucoma
  •              9.4.5.5 Other
  •          9.4.6 Glaucomas associated with inflammation, uveitis
  •          9.4.7 Glaucomas associated with ocular trauma
  •          9.4.8 Glaucomas associated with intraocular tumors
  •          9.4.9 Glaucomas associated with elevated episcleral venous pressure
  •              9.4.10 Glaucomas associated with hemorrhage
  •          9.4.11 Glaucomas following intraocular surgery
  •              9.4.11.1 Ciliary block (malignant) glaucoma
  •              9.4.11.2 Glaucomas in aphakia and pseudophakia
  •              9.4.11.3 Epithelial, fibrous, and endothelial proliferation
  •              9.4.11.4 Glaucomas associated with corneal surgery
  •              9.4.11.5 Glaucomas associated with vitreoretinal surgery
  •          9.4.15 Glaucoma in relation to systemic disease
  •          9.4.20 Other
  • 10 Differential diagnosis e.g. anterior and posterior ischemic optic neuropathy

  • 11 Medical treatment

  •      11.1 General management, indication
  •      11.2 Cholinergic drugs
  •      11.3 Adrenergic drugs
  •          11.3.1 Epinephrine
  •          11.3.2 Thymoxamine, dapiprazole
  •          11.3.3 Apraclonidine, brimonidine
  •          11.3.4 Betablocker
  •          11.3.5 Other
  •      11.4 Prostaglandins
  •      11.5 Carbonic anhydrase inhibitors
  •          11.5.1 Systemic
  •          11.5.2 Topical
  •      11.6 Osmotic treatment
  •      11.7 Treatment of bloodflow
  •      11.8 Neuroprotection
  •      11.9 Gene therapy
  •      11.13 Combination therapy
  •          11.13.1 Betablocker and pilocarpine
  •          11.13.2 Betablocker and carbon anhydrase inhibitor
  •          11.13.3 Betablocker and brimonidine
  •          11.13.4 Betablocker and prostaglandin
  •          11.13.5 Other
  •      11.14 Investigational drugs; pharmacological experiments
  •      11.15 Other drugs in relation to glaucoma
  •      11.16 Vehicles, delivery systems, pharmacokinetics, formulation
  •      11.17 Cooperation with medical therapy e.g. persistency, compliance, adherence
  •      11.20 Other
  • 12 Surgical treatment

  •      12.1 General management, indication
  •      12.2 Laser iridotomy
  •      12.3 Laser iridoplasty
  •      12.4 Laser trabeculoplasty and other laser treatment of the angle
  •      12.7 Surgical iridectomy
  •      12.8 Filtering surgery
  •          12.8.1 Without tube implant
  •          12.8.2 With tube implant or other drainage devices
  •          12.8.3 Non-perforating
  •          12.8.4 Using laser
  •          12.8.5 Other
  •          12.8.10 Woundhealing antifibrosis
  •          12.8.11 Complications, endophthalmitis
  •      12.9 Trabeculotomy, goniotomy
  •      12.10 Cyclodestruction
  •      12.11 Cyclodialysis
  •      12.12 Cataract extraction
  •          12.12.1 Intracapsular
  •          12.12.2 Extracapsular
  •          12.12.3 Phacoemulsification
  •      12.14 Combined cataract extraction and glaucoma surgery
  •          12.14.1 Intracapsular
  •          12.14.2 Extracapsular
  •          12.14.3 Phacoemulsification
  •      12.15 Capsulotomy
  •      12.16 Vitrectomy
  •      12.17 Anesthesia
  •      12.20 Other
  • 13 Therapeutic prognosis and outcome

  •      13.1 Prognostic factors
  •      13.2 Outcome
  •          13.2.1 IOP
  •          13.2.2 Visual field
  •              13.2.2.1 Progression
  •              13.2.2.2 Improvement
  •          13.2.3 Other
  • 14 Costing studies; pharmacoeconomics

  • 15 Miscellaneous




Issue 14-3

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