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Editors Selection IGR 10-4
Progression: Cirrus OCT versus Stratus OCT for RNFL progression
Comment by Esther Hoffmann on:
45781 Evaluation of Retinal Nerve Fiber Layer Progression in Glaucoma. A Comparison between Spectral-Domain and Time-Domain Optical Coherence Tomography, Leung CK-S; Chiu V; Weinreb RN et al., Ophthalmology, 2011;
This article by Leung et al. (710) evaluates the performance of spectral domain OCT (Cirrus OCT) versus time domain OCT (Stratus OCT) in the ability to detect retinal nerve fiber layer progression in patients with glaucoma. Glaucoma patients were imaged every four months for at least two years (range 24-33 months). Progression was defined as a significant negative trend in the trend analysis. RNFL improvement was evaluated, too. One hundred twenty-eight eyes of 81 patients were included. Of these, 22 eyes (measured with Cirrus) and four eyes (measured with Stratus) showed progression while zero eyes (Cirrus) and five eyes (Stratus) showed improvement in RNFL average measurements. Agreement for RNFL progression detection between TD-OCT and SD OCT was poor. Furthermore, agreement between RNFL progression detection and VF was poor.
Agreement for RNFL progression detection between TD-OCT and SD OCT was poor
It would be interesting to see whether long-term follow-up in glaucoma eyes will reveal similar results for glaucoma progression detection using SD OCT and TD OCT to this study.
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