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Editors Selection IGR 8-4
Clinical glaucoma: 24-hours IOP-control
Comment by Erik Greve on:
13885 24-hour intraocular pressure control with maximum medical therapy compared with surgery in patients with advanced open-angle glaucoma, Konstas AG; Topouzis F; Leliopoulou O et al., Ophthalmology, 2006; 113: 765e1
Konstas et al. (512) report that surgically treated patients have lower mean peak and range of IOP over 24 hrs than patients on maximal tolerated medical therapy. This prospective study was straightforward and confirms earlier results. Long ago we published that the range of IOP is considerably reduced after surgery. Assuming that the patients in both groups of Konstas et al. were comparable the results stress again an important aspect of glaucoma surgery: a flat IOP curve. Over the past thirty years the variation of IOP over time has been implicated as a possible influence on progression.
The low IOP variation in addition to a perfect compliance are particularly convincing to prefer surgical reduction of IOP in case of advanced glaucoma.
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