advertisement
Editors Selection IGR 7-2
Medical treatment: Treatment and bloodflow
Comment by Lutz Pillunat on:
12312 Effects of glaucoma drugs on ocular hemodynamics in normal tension glaucoma: A randomized trial comparing bimatoprost and latanoprost with dorzolamide [ISRCTN18873428], Zeitz O; Matthiessen ET; Reuss J et al., BMC Ophthalmology, 2005; 5: 6
The paper by Zeitz (640) et al. shows interesting results with regard to an increased peak systolic velocity and enddiastolic velocity - measured by colour doppler imaging - after application of bimatoprost, latanoprost and dorzolamide in progressive normal pressure glaucoma patients. These changes, however, proved only to be significant with regard to the PSV in the dorzolamide treated group. Whether these changes were induced by demographic differences remains unclear, as there are no details (age, sex, accompanying diseases, etc.) given.
For claiming these differences the groups examined seem to be rather small and a crossover design would have been more appropriate. Furthermore there are no data available whether systemic parameters like heart rate and blood pressure may have influenced these results.
Comments
The comment section on the IGR website is restricted to WGA#One members only. Please log-in through your WGA#One account to continue.Log-in through WGA#One