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Editors Selection IGR 15-4

Structure Tests and Anatomy: Cirrus versus stratus OCT and RNFL

Comment by Jost Jonas on:

25088 Comparison of Cirrus OCT and Stratus OCT on the ability to detect localized retinal nerve fiber layer defects in preperimetric glaucoma, Jeoung JW; Park KH, Investigative Ophthalmology and Visual Science, 2010; 51: 938-945

Find related abstracts

The morphological detection of optic nerve damage in glaucoma suspects with normal standardized visual field examinations is of high clinical importance to detect those patients who need treatment and to differentiate them from the remaining subjects. Confocal laser scanning tomography (OCT) has widely been used to examine and measure the retinal nerve fiber layer in such clinical situations. After the introduction of a new generation of OCTs into clinical practice, Jeoung and Park (216) have compared the diagnostic ability of the new Cirrus OCT versus the older Stratus OCT to detect localized retinal nerve fiber layer defects in pre-perimetric glaucoma patients. Examining 55 subjects, Jeoung and Park did not find significant differences in the diagnostic precision between both devices. This result appears to be unexpected, given the markedly higher optical quality of the new generation of spectral domain OCTs. As the authors point out in their manuscript, this result should not make one infer that the new OCT generation is not superior to the older one in detecting morphological fundus abnormalities. It may be quite in contrast, that the new OCT generation may allow developing new parameters and algorithms for the detection of a pathologic morphology including the appearance of the optic nerve head. As the authors write in their study, future studies may be focused on that goal.

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