Visual Function and Ganglion Cells

Robert N. Weinreb and Pamela A. Sample

Various visual function tests have been developed to evaluate specific retinal ganglion cell (RGC) populations. Most likely, 1. frequency-doubling technology perimetry (FDT) and various forms of motion perimetry isolate the magnocellular RGCs; 2. high-pass resolution perimetry isolates the parvocellular RGCs; and, 3. short wavelength perimetry (SWAP) isolates koniocellular RGCs. Psychophysical and histopathologic data suggest that there is no single population of RGCs that is uniformly damaged in glaucoma. (courtesy of RN Weinreb and PA Sample)