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Highlights of the Annual South African Glaucoma Society Meeting

May 26-28, 2006, Drakensberg, South Africa

Ellen Ancker

Impact of glaucoma

  • 53% of glaucoma patients have concomitant disease; 27% cardiovascular, 16% respiratory; 10% arthritis.
  • The average lifetime of a glaucoma patient is 13.5 years because of the late diagnosis.
  • 16 % of glaucoma patients with advanced VF damage have a history of hip or wrist fracture; only 10% of blind people are still working.
  • Savings in estimated costs of treatment of a POAG patient of 3% per 1 mmHg additional IOP lowering from about $17,000 per patient per year.

Risk factors

  • Risk factors need to be established for every patient individually at the time of diagnosis and need periodical re-evaluation.
  • The Star-Scoring Tool for Assessing Risk is not evidence based, a physician's experience is still necessary.
  • Diurnal IOP is not an independent risk factor in OHT.

ONH evaluation

  • Applying the ISNT rule helps to systematically evaluate the optic nerve head in glaucoma and ocular hypertension patients.
  • Look for position of the vessel trunk and notching when evaluating the ONH for progression.
  • ONH needs documentation with stereo colour photos or sequential stereo photos or digital imaging.
  • Measure optic disc size if macro or micro disc.
  • It normally takes about five years from visible retinal nerve fibre layer changes until significant visual field changes are seen.

Treatment

  • 15% of glaucoma patients miss more than 50% of their drug dosage.
  • In 40% of glaucoma patients mono therapy is not enough. When adjunctive therapy is needed use therapies with complimentary modes of action, i.e. on inflow and outflow pathways.

General

  • An acute attack of angle-closure is not glaucoma; if the optic nerve and visual field are normal, it is only an acute angle-closure.
  • Technique of laser trabeculoplasty: start at six o'clock, always rotate clockwise, burn at trabecular meshwork, take IOP six hours later, treat with CAI alpha-agonists and topical steroids for one week.
  • Consider ALT as a primary procedure in pigmentary glaucoma, pseudo-exfoliation, and above 60 years of age.
  • The first morphological changes of bilateral optic neuropathy take place in the lateral geniculate nucleus.
  •  Early aggressive treatment in glaucoma may be indicated when:
    1. presenting IOP is high;
    2. there is advanced glaucomatous damage at presentation;
    3. there is an advanced rate of glaucomatous damage progression;
    4. central vision loss is expected within lifetime;
    5. there are risk factors, such as advanced glaucoma in second eye.

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