In glaucoma, the correlation between disc topography
and visual field damage in myopic-type discs differs from that in ordinary-shaped,
non-myopic type discs.
Rho-associated protein kinase inhibitors have the potential
to be developed into a treatment modality for glaucoma.
Low-dose administration of zinc can precondition low-grade
stress in retinal ganglion cells to cope with future lethal insults.
Subjects with PACG had more advanced field loss than
those with POAG, despite the short timespan since diagnosis. The superior
hemifield was affected earlier in POAG: PACG showed no such difference.
This significant difference in the pattern of field loss between the
two disease has consequences for the pathophysiology of optic nerve
damage.
Myocilin proteins and mRNA levels do not appear to correlate
with age in normal human TM tissues. The levels of myocylin in OAG/OH
specimens are not increased. These results argue against a direct role
of myocylin, and reiterate the involvement of additonal factors in the
pathogenesis of glaucoma.
GDx parameters were capable of differentiating glaucomatous
from nonglaucomatous eyes, and the number equal to or greater than 26
was optimally 'outside normal limits' with respect to sensitivity. MD
was significantly associated with global GDx parameters.
Unilateral visual field defects by conventional white-on-white
perimetry may in fact underestimate structural as well as functional
glaucomatous damage in contralateral eyes.
The stepwise treatment-medical management, intrableb
autologous blood injection, additional sutures to the scleral flap,
necrotic bleb excision and advancement of a formical conjunctival flap,
was a useful method for managing hypotony after trabeculectomy with
MMC.
ALPI was effective in eliminating residual appositional
closure after iridotomy in eyes with plateau iris syndrome. The effect
was maintained for years, and filtration surgery avoided in the long
term.