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Top-Ten of the South East Asia Glaucoma Interest Group (SEAGIG) / Asian Angle-Closure Glaucoma Club (AACGC) Joint Congress
Seoul, Korea, September 25-27, 2008
Dong Myung Kim (l), Yong Yeon Kim (m) and Ki Ho Park (r)
- Significant RNFL loss was already present by OCT in the dischemorrhage- only eyes with apparently normal RNFL configuration by red-free photography, indicating that pre-perimetric RNFL are already present. This suggests that OCT has the potential to detect subclinical or preperimetric RNFL loss in the eyes with disc hemorrhage (Ki Ho Park, Seoul, Korea).
- Most of the patients with progressive glaucomatous damage despite an only moderately elevated or even normal IOP have altered autoregulation of ocular perfusion. Signs of reperfusion damage could even be found in the circulating lymphocytes (Joseph Flammer, Basel, Switzerland).
- Clinical assessment of the optic nerve is a cornerstone of managing patients with glaucoma, as well as those at risk for glaucoma. Glaucomatous optic disc damage can predict visual functional loss. Careful clinical examination of the optic nerve structure is essential for accurate diagnosis of glaucoma (Robert Weinreb, San Diego, CA, USA).
- The Namil Study, a glaucoma epidemiology study recently completed by the Korean Glacoma Association in Namil, Kumsan, Korea, revealed total prevalence of glaucoma at 4.7%, most of which (64%) was normal tension glaucoma. (Chan Yun Kim, Seoul, Korea)
- When primary angle closure (PAC) or primary angle-closure glaucoma (PACG) examined in a four-year period between 2004 and 2008 were compared with cases examined in a ten-year period beginning 1985, PAS formation has decreased in recent years in Japan. (Tetsuya Yamamoto, Gifu, Japan)
- When transplanted by subretinal injection, significant levels of human BDNF transduced rat bone marrow mesenchymal stem cells (MSCs) were migrated into the retina and higher levels of BDNF expression was detected. These observations may indicate that BDNF protein expression can be achieved in the retina using MSCs as a gene transfer vehicle. (Chan Kee Park, Seoul, Korea)
- Potential applications of tissue bioengineering using nanotechnology in the near future deal with biomechanics, new drug delivery systems, 'smart bomb' drugs, neural prosthetics, microsensors to measure intraocular pressure and small vessel blood flow, and cell and tissue regeneration, such as using stem cells. (Robert Ritch, New York, NY, USA).
- A dramatic loss of iris volume, a 12% loss per each millimeter of pupil diameter increase, was shown by Visante anterior segment OCT. This loss of iris area is significantly less in those with ACG compared to non-ACG, suggesting that one reason that persons with ACG develop closure is a failure of their iris to shrink as much with dilation. (Harry Quigley, Baltimore, MD, USA)
- Three new non-contact devices, the scanning peripheral anterior chamber depth analyzer (SPAC), IOL Master and the Visante anterior segment OCT (AS-OCT), showed low specificity which may limit the usefulness of these devices in screening for narrow angles. (Tin Aung, Singapore)
- Recent surgical trials are gradually defining an important and increasing role for lens extraction in the surgical management of chronic angle-closure glaucoma, whether alone or in combination with other glaucoma procedures. (Clement Tham, Hong Kong)
