Top-ten European Glaucoma Society Meeting
Madrid, Spain, September 12-17, 2010
Francisco Goni, Fotis Topouzis
Intraocular Pressure (IOP) rises during night time. Both Systolic
Blood Pressure (SBP) and Diastolic Blood Pressure (DBP) are lower during
night time. Ocular Perfusion Pressure (OPP) is lower during night time.
Glaucoma medications should be evaluated for 24 hour effectiveness.
A single measurement at office hours is still insufficient. The
optimal times for IOP measurement are not known. In the future 24 hours
IOP measurements will become a standard in our glaucoma patients' care.
(Weinreb, La Jolla, CA, USA)
Carbonic anhydrase inhibitors better regulate IOP at night, as
add-ons toon prostaglandins, compared with beta blockers. (Weinreb,
La Jolla, CA, USA)
Risk factors for OAG are statistically associated with the development
of OAG whereas prognostic factors for OAG are statistically associated
with the progression of OAG. Factors such as disc parameters and visual
field indices are not risk factors, because they are part of glaucoma
definition and therefore should be called predictive factors. (Coleman,
Los Angeles, CA, USA)
About 20% of untreated patients have a rather fast rate of progression
of 1dB/year or faster. In newly diagnosed glaucoma patients it is recommended
to do 6 VFs in the first two years to rule out fast progression. (Chauhan,
Halifax, Canada)
Age and stage of damage are crucial in clinical decision making
(Heijl, Malmo, Sweden)
The impact of OHT/POAG on the quality of life increases with the
severity of the disease. Whereas OHT and early POAG do not show major
effects on quality of life, moderate and advanced POAG do. (Pfeiffer,
Mainz, Germany)
IIt appears that at least 50% of the field must be lost before glaucomatous
patients will be aware of a loss of visual function. VFI correlates
better than MD with the self perception of visual impairment in a patient
suffering from glaucoma. (Gandolfi, Parma, Italy)
Using adjusted IOP does not improve predictive power of the OHTS
risk model. Adjusting IOP for CCT is trying to add precision in a very
'noisy' measurement; therefore IOP should not be adjusted for CCT.
(Brandt, Sacramento, USA)
In the AGIS, long-term IOP fluctuation in patients with low mean
IOP, older age, longer follow-up and higher number of interventions
were all predictive of VF progression. (Caprioli, Los Angeles, CA, USA)
Ocular hypertensives with the highest risk levels of developing
glaucoma are expected to benefit more from an early hypotensive treatment.
(Parrish, Miami, FL, USA)